產(chǎn)品介紹

Agitoxin-2 

Blocker of K_v1.1 and K_v1.3 channels

鉀離子通道K_v1.1 和K_v1.3阻斷劑

Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated K_v1.3 and K_v1.1 channels. inhibits K_v1.3 with an IC₅₀ value of around 200 pM and K_v1.1 with an IC₅₀ value of around 140 pM. This peptide toxin was originally isolated from the venom of the Israeli scorpion L. quinquestriatus hebraeus.

技術(shù)資料

氨基酸序列：

 Gly-Val-Pro-Ile-Asn-Val-Ser-Cys⁸-Thr-Gly-Ser-Pro-Gln-Cys¹⁴-Ile-Lys-Pro-Cys¹⁸-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys²⁸-Met-Asn-Arg-Lys-Cys³³-His-Cys³⁵-Thr-Pro-Lys-OH

二硫鍵：Cys⁸-Cys²⁸; Cys¹⁴-Cys³³; Cys¹⁸-Cys³⁵ 

長(zhǎng)度 (aa)：  38

分子式： C₁₆₉H₂₇₈N₅₄O₄₈S₈ 

分子量：4090.89 Da

外觀： White lyophilized solid

可溶性：water and saline buffer

CAS 號(hào)： 168147-41-9

來(lái)源： Synthetic 

純度： > 97 %

產(chǎn)品信息